Litcius/Paper detail

A functional 2D MXene–DNA hybrid hydrogel for portable detection of blood disorder biomarker thrombin in human plasma

Vinod Morya, Dhiraj Bhatia, Chinmay Ghoroi, Amit K. Yadav

2025Journal of Materials Chemistry B13 citationsDOI

Abstract

) of 0.98, indicating excellent linearity and reliability across the tested range. The concept was successfully demonstrated, achieving a relative standard deviation (RSD) of 8-10% for thrombin detection in artificial samples, indicating excellent performance. This robust technique holds promise for biomedical sensing devices, allowing customization for detecting various target molecules using specific aptamers.

Topics & Concepts

BiomarkerMaterials scienceHuman plasmaThrombinHuman bloodDNANanotechnologyChemistryMedicineBiochemistryChromatographyImmunologyPlateletPhysiologyMXene and MAX Phase MaterialsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery