The <scp>u</scp>se of Vaccinia Immune Globulin in the Treatment of Severe Mpox. Virus Infection in Human Immunodeficiency Virus/AIDS
Andrea K Thet, Paul J. Kelly, Sabirah N Kasule, Anish Shah, Arpan Chawala, Amber Latif, Sridhar Chilimuri, Cosmina B Zeana
Abstract
We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an adjunct for severe disease in immunocompromised hosts.
Topics & Concepts
VacciniaMedicineVirusVirologyImmunologyImmune systemPoxviridaeOrthopoxvirusAntibodyHuman immunodeficiency virus (HIV)DiseaseImmunopathologyBiologyRecombinant DNAInternal medicineGeneBiochemistryPoxvirus research and outbreaksBacillus and Francisella bacterial researchHerpesvirus Infections and Treatments