Litcius/Paper detail

Neuroprotective effects of dietary plants and phytochemicals against radiation-induced cognitive and behavioral deficits: a comprehensive review of evidence and prospects for future research

Shamprasad Varija Raghu, Avinash K. Kudva, Rajanikant Golgodu Krishnamurthy, Jayesh Mudgal, Thomas George, Manjeshwar Shrinath Baliga

2023Food & Function15 citationsDOI

Abstract

, and phytochemicals such as vitamin E, corilagin, curcumin, resveratrol, and ursolic acid have demonstrated potential in mitigating radiation-induced damage to the CNS. Furthermore, preliminary studies have indicated that alpha-tocopherol and the micronutrient selenium have neuroprotective effects in cancer survivors previously treated with radiation to the brain. This review focuses exclusively on behavioral outcomes to assess the impact of ionizing radiation on the CNS and the effectiveness of dietary plants and phytochemicals as neuroprotective agents against radiation-induced neuronal damage.

Topics & Concepts

NeuroprotectionCognitionNeurosciencePsychologyMedicineAnesthesia and Neurotoxicity ResearchBiochemical effects in animalsMedicinal Plants and Bioactive Compounds