Prognostic value of peripheral blood T lymphocyte subsets in clear cell renal cell carcinoma
Yihong Zhou, Dong Jiang, Xi Chu, Wenjie Cheng, Shuchang Huang, Jinhua Wang, Hao Zhang, Min Liu, Yuxin Tang, Yingbo Dai
Abstract
BACKGROUND: To date, few studies have evaluated the role of peripheral blood T lymphocyte subsets in patients with clear cell renal cell carcinoma (ccRCC). Here we measured the levels of peripheral blood T lymphocyte subsets and evaluated its prognostic value in ccRCC. METHODS: Data from 122 patients with RCC from January 2018 to January 2020 were collected. Preoperative peripheral blood T lymphocyte subsets and medical records were analyzed. Kaplan-Meier cures and log rank test were used for analyzing overall survival (OS). Univariate and multivariate survival analyses were underwent by performing the Cox proportional hazards models. Correlations were tested by Pearson's correlation analysis. RESULTS: ratio (P<0.001, r=-0.398 and P=0.012, r=-0.280, respectively). CONCLUSIONS: ratio in peripheral blood are independent predictors for patients with ccRCC.