Discovery of ingenane and jatrophane diterpenoids from Euphorbia esula as inhibitors of RANKL-induced osteoclastogenesis
Shengheng Yuan, Yuting Zhang, Pei Hua, Huihao Zhou, Jun Xu, Qiong Gu
Topics & Concepts
RANKLEuphorbiaceaeIC50EuphorbiaStereochemistryChemistryBiologyBiochemistryIn vitroBotanyReceptorActivator (genetics)Bioactive Natural Diterpenoids ResearchCell death mechanisms and regulationNF-κB Signaling Pathways