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VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients

A. Nazmul H. Khan, Tiffany R. Emmons, William J. Magner, Emad Alqassim, Kelly L. Singel, Jason Ricciuti, Kevin H. Eng, Kunle Odunsi, Thomas B. Tomasi, Kelvin H. Lee, Scott I. Abrams, Circe Mesa, Brahm H. Segal

2022Cancer Immunology Immunotherapy18 citationsDOIOpen Access PDF

Topics & Concepts

Myeloid-derived Suppressor CellOvarian cancerTumor microenvironmentCancer researchCytotoxic T cellImmune systemOvarian tumorCD8MyeloidMacrophage polarizationImmunologyBiologyInflammationMedicineCancerMacrophageInternal medicineIn vitroSuppressorBiochemistryImmune cells in cancerReproductive System and PregnancyImmune Cell Function and Interaction
VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients | Litcius