PI3K/Akt Signaling Pathway Ameliorates Oxidative Stress-Induced Apoptosis upon Manganese Exposure in PC12 Cells
Yanli Tan, Hong Cheng, Cheng Su, Pan Chen, Xiaobo Yang
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayLY294002ChemistryApoptosisSuperoxide dismutaseMalondialdehydeDownregulation and upregulationOxidative stressMolecular biologyCell biologyBiologyBiochemistryGeneFOXO transcription factor regulationCell death mechanisms and regulationHeavy Metal Exposure and Toxicity