Dnaapler: A tool to reorient circular microbialgenomes
George Bouras, Susanna R. Grigson, Bhavya Papudeshi, Vijini Mallawaarachchi, Michael J. Roach
Abstract
Microorganisms found in natural environments are fundamental components of ecosystems and play vital roles in various ecological processes.Studying their genomes can provide valuable insights into the diversity, functionality, and evolution of microbial life, as well as their impacts on human health.Once the genetic material is extracted from environmental samples, it undergoes sequencing using technologies like whole genome sequencing (WGS).The raw sequence data is then analysed, and computational methods are applied to assemble the fragmented sequences and reconstruct the complete microbial genomes (Wick et al.,
Topics & Concepts
BiologyEvolutionary biologyComputational biologyBacteriophages and microbial interactionsGenomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology