Anaphylaxis after Treatment with an Endodontic Material Containing Polyethylene Glycol
Marie Alnæs, Torgeir Storaas, Hilde Kristin Vindenes, Anne Berit Guttormsen, Lars Björkman
Abstract
Polyethylene glycol (PEG) is sometimes included in temporary endodontic filling materials to modify viscosity. PEG is considered a low hazard chemical, but parenteral PEG exposure is associated with a risk of anaphylaxis. We report 2 cases of anaphylaxis after treatment with an endodontic temporary filling material containing PEG. One patient survived after hospital treatment, but the second case was fatal. Extensive investigations were needed to find the culprit. Allergic reactions to PEG are increasingly reported and have significant implications for the patient. Precautionary measures are discussed.
Topics & Concepts
Polyethylene glycolAnaphylaxisMaterials scienceDentistryMedicineOrganic chemistryChemistryAllergyImmunologyContact Dermatitis and AllergiesFood Allergy and Anaphylaxis ResearchDrug-Induced Adverse Reactions