Litcius/Paper detail

The Selective Role of Open and Endoscopic Approaches for Sinonasal Malignant Tumours

Fernando López, Jatin P. Shah, Jonathan J. Beitler, Carl H. Snyderman, Valerie J. Lund, Cesare Piazza, Antti Mäkitie, Orlando Guntinas‐Lichius, Juan P. Rodrigo, Luiz Paulo Kowalski, Miquel Quer, Ashok R. Shaha, Akihiro Homma, Álvaro Sanabria, Renata Ferrarotto, Anne W.M. Lee, Victor Lee, Alessandra Rinaldo, Alfio Ferlito

2022Advances in Therapy21 citationsDOIOpen Access PDF

Abstract

Endoscopic endonasal surgery has been demonstrated to be effective in the treatment of selected cases of sinonasal cancers. However, in cases of locally advanced neoplasms, as well as recurrences, the most appropriate approach is still debated. The present review aims to summarize the current state of knowledge on the utility of open approaches to resect sinonasal malignant tumours. Published comparative studies and meta-analyses suggest comparable oncological results with lower morbidity for the endoscopic approaches, but selection biases cannot be excluded. After a critical analysis of the available literature, it can be concluded that endoscopic surgery for selected lesions allows for oncologically safe resections with decreased morbidity. However, when endoscopic endonasal surgery is contraindicated and definitive chemoradiotherapy is not appropriate, craniofacial and transfacial approaches remain the best therapeutic option.

Topics & Concepts

MedicineSurgeryChemoradiotherapyEndoscopic surgeryEndoscopyEndoscopic treatmentRadiation therapyHead and Neck Surgical OncologySinusitis and nasal conditionsMeningioma and schwannoma management