Recent advances and perspectives in biosynthesis of paclitaxel: key enzymes and intermediates
Qingqing Chen, Xin Qi, Sheng Dong, Xin Ge, Xiao Men, Haibo Zhang
Topics & Concepts
PaclitaxelBiosynthesisComputational biologyBiologyEnzymeBiotechnologyDrug discoverySynthetic biologyDrug developmentBiochemistryHeterologousMetabolic engineeringKey (lock)ChemistryMechanism (biology)FermentationTaxusSustainable productionProcess (computing)Heterologous expressionBiochemical engineeringDrugProduction (economics)Anticancer drugCancer Treatment and PharmacologyMicrobial Natural Products and BiosynthesisPlant biochemistry and biosynthesis