Re-evaluation of the hCMEC/D3 based in vitro BBB model for ABC transporter studies
Viktor Balzer, Pascal Poc, Elena Puris, Stefan F. Martin, Maryam Aliasgari, Seppo Auriola, Gert Fricker
Topics & Concepts
Abcg2Paracellular transportTranscellularP-glycoproteinATP-binding cassette transporterEffluxTransporterBlood–brain barrierIn vitroPharmacologyChemistryMediated transportTight junctionIn vivoCell biologyMultiple drug resistancePermeability (electromagnetism)BiologyBiochemistryNeuroscienceMembraneGeneAntibioticsBiotechnologyCentral nervous systemDrug Transport and Resistance MechanismsProtein Interaction Studies and Fluorescence AnalysisTrace Elements in Health