Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats
Li Lin, Haiyan Gan, Huaqian Jin, Yan Fang, Yan Yang, Jianping Zhang, Xiaowei Hu, Lisheng Chu
Topics & Concepts
MicrogliaNeurogenesisPharmacologyVascular endothelial growth factorMedicineIschemiaAngiogenesisNeuroprotectionReperfusion injuryMacrophage polarizationInflammationEndocrinologyInternal medicineBiologyMacrophageNeuroscienceBiochemistryVEGF receptorsIn vitroNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerNeurological Disease Mechanisms and Treatments