Triphenylphosphonium-functionalized dimeric BODIPY-based nanoparticles for mitochondria-targeting photodynamic therapy
Chanwoo Kim, Duy Khuong, Joomin Lee, Jinwoong Jo, Soyeon Kim, Isabel Wen Badon, Jong Min Lim, Hojoong Kim, Jaesung Yang
Abstract
This study reports the synthesis, characterization, and photodynamic therapy activity of two orthogonal BODIPY dimers functionalized with TPP cations for mitochondrial targeting.
Topics & Concepts
BODIPYPhotodynamic therapyCombinatorial chemistryNanoparticleChemistryMitochondrionCharacterization (materials science)FluorescenceMaterials scienceNanotechnologyBiochemistryOrganic chemistryPhysicsQuantum mechanicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPorphyrin and Phthalocyanine Chemistry