Perfluorooctanoic acid disrupts thyroid-specific genes expression and regulation via the TSH-TSHR signaling pathway in thyroid cells
Yatao Du, Chaojie Chen, Guangdi Zhou, Zhenzhen Cai, Qiuhong Man, Baolin Liu, Weiye Charles Wang
Topics & Concepts
ThyroglobulinInternal medicineEndocrinologyThyroid peroxidaseThyroidSodium-iodide symporterPerfluorooctanoic acidThyroid-stimulating hormoneChemistryHormoneCyclic adenosine monophosphateCREBTranscription factorReceptorSignal transductionBiologySymporterBiochemistryMedicineGeneTransporterPer- and polyfluoroalkyl substances researchBirth, Development, and HealthChemical Analysis and Environmental Impact