Sex-dependent membranopathy in stored human red blood cells
Ewa Szczęsny-Małysiak, Tasnim Mohaissen, Katarzyna Bułat, Magdalena Kaczmarska, Aleksandra Wajda, Katarzyna M. Marzec
Abstract
Over the past years, concern has been raised over the impact of red blood cell (RBC) alterations, related to prolonged hypothermic storage, on patient safety. 2] However, these results, as well as those of other groups were mainly obtained from pRBC of male donors, or the sex of donors was not specified. Recently, it has also been suggested that RBC from females are less prone to storage lesion and age slower than male erythrocytes 9,10 but these reports were mainly focused on metabolic and functional RBC analysis.
Topics & Concepts
Blood preservationAndrologyBiologyMedicineErythrocyte Function and PathophysiologyHemoglobinopathies and Related DisordersBlood groups and transfusion