PTP70-2, a novel polysaccharide from Polygala tenuifolia, prevents neuroinflammation and protects neurons by suppressing the TLR4-mediated MyD88/NF-κB signaling pathway
Haiyun Chen, Jing Zhong, Jianxuan Li, Zhiwei Zeng, Qian Yu, Chunyan Yan
Topics & Concepts
NeuroinflammationTLR4NeuroprotectionProinflammatory cytokineNF-κBCell biologyChemistryLipopolysaccharideSignal transductionNeurotoxicityInflammationPharmacologyBiologyImmunologyToxicityOrganic chemistryNeuroinflammation and Neurodegeneration MechanismsGalectins and Cancer BiologySeaweed-derived Bioactive Compounds