Litcius/Paper detail

The regulatory framework for microbiome-based therapies: insights into European regulatory developments

Julie Rodriguez, Magali Cordaillat‐Simmons, Bruno Pot, Céline Druart

2025npj Biofilms and Microbiomes44 citationsDOIOpen Access PDF

Abstract

The emergence of a broad spectrum of microbiome-based therapies has triggered changes in European regulatory frameworks. The first part of the review describes these innovative therapies. The second part provides an overview of the current framework and key changes introduced by the Regulation on substances of human origin (SoHO) for the development of microbiome-based therapies, highlighting the need of microbiome regulatory science to unlock the full potential of microbiome-based therapies.

Topics & Concepts

Regulatory scienceMicrobiomeComputational biologyBiologyBioinformaticsEcologyGut microbiota and healthClostridium difficile and Clostridium perfringens researchProbiotics and Fermented Foods