The selective activator protein-1 inhibitor T-5224 regulates the IRF4/MYC axis and exerts cooperative antimyeloma activity with bortezomib
Sishi Tang, Fangrong Zhang, Li J, Hang Dong, Qin Yang, Jing Liu, Yunfeng Fu
Topics & Concepts
JUNBIRF4BortezomibCancer researchCell growthApoptosisMolecular biologyChemistryTranscription factorBiologyMultiple myelomaImmunologyBiochemistryGeneMultiple Myeloma Research and TreatmentsProtein Degradation and InhibitorsUbiquitin and proteasome pathways