Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer
Peter M.K. Westcott, Nathan Sacks, Jason M. Schenkel, Zackery A. Ely, Olivia Smith, Haley Hauck, Alex M. Jaeger, Daniel Zhang, Coralie M. Backlund, Mary C. Beytagh, J. J. Patten, Ryan Elbashir, George Eng, Darrell J. Irvine, Omer H. Yilmaz, Tyler Jacks
Topics & Concepts
Microsatellite instabilityImmune systemPriming (agriculture)Colorectal cancerImmunotherapyCancerEvasion (ethics)BiologyImmunologyCancer researchImmune toleranceT cellMedicineGeneGeneticsMicrosatelliteAlleleBotanyGerminationImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology