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BL-B01D1, a first-in-class EGFR–HER3 bispecific antibody–drug conjugate, in patients with locally advanced or metastatic solid tumours: a first-in-human, open-label, multicentre, phase 1 study

Yuxiang Ma, Yan Huang, Yuanyuan Zhao, Shen Zhao, Jinhui Xue, Yunpeng Yang, Wen‐Feng Fang, Ye Guo, Yaqian Han, Kunyu Yang, Yongsheng Li, Jun Yang, Zhenming Fu, Gang Chen, Likun Chen, Ningning Zhou, Ting Zhou, Yaxiong Zhang, Huaqiang Zhou, Qianwen Liu, Yi Zhu, Hai Zhu, Sa Xiao, Li Zhang, Hongyun Zhao

2024The Lancet Oncology121 citationsDOI

Topics & Concepts

ConjugateMedicineDrugAntibody-drug conjugateOpen labelPhases of clinical researchAntibodyBispecific antibodyOncologyPharmacologyCancer researchInternal medicineMonoclonal antibodyClinical trialImmunologyMathematicsMathematical analysisHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchColorectal Cancer Treatments and Studies
BL-B01D1, a first-in-class EGFR–HER3 bispecific antibody–drug conjugate, in patients with locally advanced or metastatic solid tumours: a first-in-human, open-label, multicentre, phase 1 study | Litcius