Mammea type coumarins isolated from Calophyllum brasiliense induced apoptotic cell death of Trypanosoma cruzi through mitochondrial dysfunction, ROS production and cell cycle alterations
Karla Daniela Rodríguez‐Hernández, Ignacio Martínez, Ricardo Reyes‐Chilpa, Bertha Espinoza
Topics & Concepts
Trypanosoma cruziBenznidazoleReactive oxygen speciesChagas diseaseApoptosisChemistryProgrammed cell deathPhosphatidylserineIntracellularCell cycle checkpointBiochemistryAutophagyBiologyPharmacologyCell cycleVirologyParasite hostingMembraneComputer sciencePhospholipidWorld Wide WebTrypanosoma species research and implicationsResearch on Leishmaniasis StudiesPlant-derived Lignans Synthesis and Bioactivity