Ensuring Ethical Postprogression Therapy for Patients in Randomized Trial Control Arms
Edward R. Scheffer Cliff, Aaron S. Kesselheim, William B. Feldman
Abstract
@Eddie_Cliff et al explore the scientific & ethical reasons why patients randomized to the control arm of trials should 'crossover' to receive the investigational therapy if their disease progresses
Topics & Concepts
MedicineRandomized controlled trialSurgeryEthics in Clinical ResearchBiomedical Ethics and RegulationHealth Systems, Economic Evaluations, Quality of Life