Brønsted base-catalyzed assembly of sulfochromeno[4,3- <i>b</i> ]pyrrolidines <i>via</i> tandem [3 + 2] cycloaddition–SuFEx click reaction of ethenesulfonyl fluorides and <i>o</i> -hydroxyaryl azomethines
Fang Zhang, Qichao Zhang, Pei Xie, Lin He, Zhihua Cai, Guangfen Du
Abstract
o -Hydroxyaryl azomethine ylides react with ethenesulfonyl fluorides via a tandem [3 + 2] cycloaddition–SuFEx click process to produce sulfochromeno[4,3- b ]pyrrolidines in high yields.
Topics & Concepts
ChemistryCycloadditionTandemCatalysisBase (topology)Medicinal chemistryCombinatorial chemistryOrganic chemistryMathematical analysisMathematicsMaterials scienceComposite materialClick Chemistry and ApplicationsFluorine in Organic ChemistrySynthesis and Catalytic Reactions