Grafting resveratrol onto mesoporous silica nanoparticles towards efficient sustainable immunoregulation and insulin resistance alleviation for diabetic periodontitis therapy
Yujie Tan, Jing Feng, Yu Xiao, Chongyun Bao
Abstract
B signaling pathway. This study also focused on the auxiliary effect of MSN-RSV on alleviating insulin resistance (IR) and controlling glucose metabolism. In brief, the study has provided a potential alternative strategy for DP therapy. It is also helpful for future intensive research topics like the immunoregulatory mechanisms in the bidirectional relationship between diabetes and periodontitis.
Topics & Concepts
ResveratrolInsulin resistanceAMPKMacrophage polarizationPeriodontitisMesoporous silicaPharmacologyCombination therapyInsulinMaterials scienceMedicineChemistryKinaseMacrophageMesoporous materialProtein kinase ABiochemistryInternal medicineCatalysisIn vitroOral microbiology and periodontitis researchSalivary Gland Disorders and FunctionsAntimicrobial Peptides and Activities