Computational Analysis of the Mechanism of Nonenzymatic Peptide Bond Cleavage at the C-Terminal Side of an Asparagine Residue
Koichi Kato, Tomoki Nakayoshi, Yoshinobu Ishikawa, Eiji Kurimoto, Akifumi Oda
Abstract
) were sufficiently low for the reactions to occur under normal physiological conditions.
Topics & Concepts
DeamidationChemistrySuccinimideSide chainPeptide bondPeptideResidue (chemistry)Cleavage (geology)StereochemistryBond cleavageAsparagineCysteineAmino acidCatalysisBiochemistryOrganic chemistryEnzymeEngineeringFracture (geology)Geotechnical engineeringPolymerProtein Structure and DynamicsConnexins and lens biologyEnzyme Structure and Function