Efficient Suppression of NRAS-Driven Melanoma by Co-Inhibition of ERK1/2 and ERK5 MAPK Pathways
Christian Adam, Lorenza Fusi, Neele Weiss, Simon Goller, Katharina Meder, Verena Frings, Hermann Kneitz, Matthias Goebeler, Roland Houben, David Schrama, Marc Schmidt
Topics & Concepts
Neuroblastoma RAS viral oncogene homologMAPK/ERK pathwayMelanomaCancer researchMedicineChemistryInternal medicineSignal transductionCancerKRASBiochemistryColorectal cancerMelanoma and MAPK PathwaysCutaneous Melanoma Detection and ManagementCancer Mechanisms and Therapy