Transdermal microneedle integrating a biomimetic self-enhancing Fenton reaction nano-reactor for alleviating rheumatoid arthritis by inflammatory microenvironment remodeling
Ying Gao, Xuejun Chen, Lin Liu, Jingya Xiu, Yufei Wen, Chunrong Yang, Degong Yang, Fen Yao
Abstract
This study designed and synthesized an innovative biomimetic self-enhancing Fenton reaction nano-reactor, and utilized microneedles for the transdermal delivery, providing a scientific and effective new strategy for the precise treatment of RA.
Topics & Concepts
Rheumatoid arthritisTransdermalNano-InflammationChemistryMedicinePharmacologyImmunologyMaterials scienceComposite materialAdvancements in Transdermal Drug DeliveryProtein Interaction Studies and Fluorescence AnalysisToxin Mechanisms and Immunotoxins