Point-of-care manufacturing of anti-CD19 CAR-T cells using a closed production platform: Experiences of an academic in Thailand
Sudjit Luanpitpong, Phatchanat Klaihmon, Montira Janan, Smith Kungwankiattichai, Weerapat Owattanapanich, Chutima Kunacheewa, Supasorn Chanthateyanonth, Nawapotch Donsakul, Yaowalak U‐pratya, Thanatphak Warindpong, Janejira Kittivorapart, Parichart Permpikul, Surapol Issaragrisil
Abstract
. The POC manufacturing and quality control settings herein could be applied to other CAR-T cell products and may benefit other academics, especially those in developing countries, making CAR-T cells more accessible.
Topics & Concepts
Production (economics)CD19Point of carePoint (geometry)Manufacturing engineeringComputer scienceBusinessOperations managementMathematicsMedicineEngineeringNursingImmunologyEconomicsAntigenMicroeconomicsGeometryCAR-T cell therapy researchNanowire Synthesis and Applications