Simultaneous dendritic cells targeting and effective endosomal escape enhance sialic acid-modified mRNA vaccine efficacy and reduce side effects
Xueying Tang, Jiashuo Zhang, Dezhi Sui, Qiongfen Yang, Tianyu Wang, Zihan Xu, Xiaoya Li, Xin Gao, Xinyang Yan, Xinrong Liu, Yanzhi Song, Yihui Deng
Topics & Concepts
EndosomeEndoplasmic reticulumMessenger RNATransfectionCell biologyChemistryEndocytosisSialic acidBiologyBiochemistryCellGeneImmunotherapy and Immune ResponsesRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques