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LBA38 BNT211-01: A phase I trial to evaluate safety and efficacy of CLDN6 CAR T cells and CLDN6-encoding mRNA vaccine-mediated in vivo expansion in patients with CLDN6-positive advanced solid tumours

A. Mackensen, J.B.A.G. Haanen, Christian Koenecke, W. Alsdorf, E. Wagner-Drouet, D. Heudobler, P. Borchmann, C. Bokemeyer, S. Klobuch, E. Smit, F. Müller, A. Desuki, F. Lüke, E. Wiegert, C. Flemmig, Catrine Schulz-Eying, B. Rengstl, L. Preussner, Ö. Türeci, U. Sahin

2022Annals of Oncology30 citationsDOI

Topics & Concepts

MedicineCytokine release syndromeFludarabineImmunologyGastroenterologyInternal medicineT cellChimeric antigen receptorImmune systemCyclophosphamideChemotherapyCAR-T cell therapy researchImmunotherapy and Immune ResponsesExtracellular vesicles in disease
LBA38 BNT211-01: A phase I trial to evaluate safety and efficacy of CLDN6 CAR T cells and CLDN6-encoding mRNA vaccine-mediated in vivo expansion in patients with CLDN6-positive advanced solid tumours | Litcius