Direct access to 2-aryl-3-cyanothiophenes by a base-catalyzed one-pot two-step three-component reaction of chalcones with benzoylacetonitriles and elemental sulfur
Nang Duy Lai, Thu Trang Nguyen, Thu Trang Nguyen, Nhu Ngan Ha Nguyen, Pascal Retailleau, Dinh Hung Mac, Thanh Bình Nguyễn, Thanh Bình Nguyễn
Abstract
3-Cyanothiophenes could be obtained via a three-component reaction of chalcones with benzoylacetonitriles and sulfur.
Topics & Concepts
ChemistryArylSulfurCatalysisBase (topology)Component (thermodynamics)Organic chemistryCombinatorial chemistryMathematical analysisMathematicsThermodynamicsAlkylPhysicsSulfur-Based Synthesis TechniquesClick Chemistry and ApplicationsMulticomponent Synthesis of Heterocycles