Emerging targeted protein degradation tools for innovative drug discovery: From classical PROTACs to the novel and beyond
Yue Zhong, Fanglian Chi, Hanyu Wu, Yunxiao Liu, Zhancheng Xie, Wenlong Huang, Wei Shi, Hai Qian
Topics & Concepts
DruggabilityDrug discoveryProtein degradationUbiquitinProteasomeComputational biologyChemistryBiochemical engineeringNanotechnologyEngineeringBiochemistryBiologyMaterials scienceGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis