Transcriptional Response of <i>Wolbachia</i> to Dengue Virus Infection in Cells of the Mosquito Aedes aegypti
Michael Leitner, Cameron Bishop, Sassan Asgari
Abstract
Aedes aegypti is a vector of several pathogenic viruses, including dengue, Zika, chikungunya, and yellow fever viruses, which are of importance to human health. Wolbachia is an endosymbiotic bacterium currently used in transinfected mosquitoes to suppress replication and transmission of dengue viruses. However, the mechanism of Wolbachia -mediated virus inhibition is not fully understood.
Topics & Concepts
WolbachiaAedes aegyptiChikungunyaDengue feverVirologyBiologyVector (molecular biology)Dengue virusZika virusAedesTransmission (telecommunications)ArbovirusYellow feverVirusViral replicationHost (biology)GeneticsGeneEcologyEngineeringElectrical engineeringRecombinant DNALarvaInsect symbiosis and bacterial influencesMosquito-borne diseases and controlInsect and Pesticide Research