Inhibition of ferroptosis ameliorates hypertensive nephropathy through p53/Nrf2/p21 pathway by Taohongsiwu decoction: Based on network pharmacology and experimental validation
Ting Xie, Zhenyu Bai, Zedong Chen, Huiyu Liang, Tianhao Liu, Lai Kwan Lam, Pengli Xu, Pengcheng Xie, Liguo Chen, Ya Xiao, Ya Xiao
Topics & Concepts
PharmacologyDownregulation and upregulationMalondialdehydeMedicineSuperoxide dismutaseOxidative stressCatalaseNephropathyHypertensive NephropathyCancer researchKidneyChemistryInternal medicineEndocrinologyDiabetic nephropathyBiochemistryGeneDiabetes mellitusFerroptosis and cancer prognosisGDF15 and Related BiomarkersClusterin in disease pathology