Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells
Jiaming Yuan, Chenjuan Yao, Jing Tang, Yingqi Liu, Chunyan Huang, Shali Yu, Haiyan Wei, Yu Han, Gang Chen
Topics & Concepts
Unfolded protein responseEndoplasmic reticulumASK1Protein kinase RProtein kinase ACell biologyp38 mitogen-activated protein kinasesGlucose-regulated proteinKinaseDownregulation and upregulationChemistryMAPK/ERK pathwayMAP kinase kinase kinaseBiologyMitogen-activated protein kinase kinaseBiochemistryGeneEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyRNA regulation and disease