Synthesis and biological evaluation of novel hybrid compounds bearing pyrazine and 1,2,4-triazole analogues as potent antitubercular agents
S. R. NAIK, Dinesha Puttachari, A. L. Vanishree, Udayakumar Dalimba, Varsha Prakash Shetty, C.P. Prabhu, Vijaya Kumar Deekshit
Abstract
In this study, we synthesized a series of hybrid compounds (T1–T18) containing pyrazine and 1,2,4-triazole moiety and assessed their effectiveness against mycobacterium tuberculosis .
Topics & Concepts
PyrazineTriazoleCombinatorial chemistryBearing (navigation)ChemistryStereochemistryOrganic chemistryComputer scienceArtificial intelligenceSynthesis and biological activitySynthesis and Biological EvaluationSynthesis and Characterization of Heterocyclic Compounds