Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
Christopher J. Draper-Joyce, Rebecca F. Bhola, Jinan Wang, Apurba Bhattarai, Thi Nguyen, India Cowie-Kent, Kelly O’Sullivan, Ling Yeong Chia, Hariprasad Venugopal, Céline Valant, David M. Thal, Denise Wootten, Nicolas Panel, Jens Carlsson, MacDonald J. Christie, Paul J. White, Peter J. Scammells, Lauren T. May, Patrick M. Sexton, Radostin Danev, Yinglong Miao, Alisa Glukhova, Wendy L. Imlach, Arthur Christopoulos
Topics & Concepts
Allosteric regulationChemistryAllosteric modulatorAdenosinePharmacologyAdenosine receptorNeuropathic painAnalgesicTransmembrane domainLigand (biochemistry)ReceptorBiochemistryMedicineAgonistReceptor Mechanisms and SignalingPharmacological Receptor Mechanisms and EffectsNeuroscience and Neuropharmacology Research