Litcius/Paper detail

Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia

Christopher J. Draper-Joyce, Rebecca F. Bhola, Jinan Wang, Apurba Bhattarai, Thi Nguyen, India Cowie-Kent, Kelly O’Sullivan, Ling Yeong Chia, Hariprasad Venugopal, Céline Valant, David M. Thal, Denise Wootten, Nicolas Panel, Jens Carlsson, MacDonald J. Christie, Paul J. White, Peter J. Scammells, Lauren T. May, Patrick M. Sexton, Radostin Danev, Yinglong Miao, Alisa Glukhova, Wendy L. Imlach, Arthur Christopoulos

2021Nature159 citationsDOIOpen Access PDF

Topics & Concepts

Allosteric regulationChemistryAllosteric modulatorAdenosinePharmacologyAdenosine receptorNeuropathic painAnalgesicTransmembrane domainLigand (biochemistry)ReceptorBiochemistryMedicineAgonistReceptor Mechanisms and SignalingPharmacological Receptor Mechanisms and EffectsNeuroscience and Neuropharmacology Research