Pyridine-pyrazole based Al(<scp>iii</scp>) ‘turn on’ sensor for MCF7 cancer cell imaging and detection of picric acid
Sayan Saha, Avik De, Arijit Ghosh, Avik Ghosh, Kaushik Bera, Krishna Sundar Das, Sohel Akhtar, Nakul C. Maiti, Abhijit K. Das, Benu Brata Das, Raju Mondal
Abstract
DPC-Al complex can also be utilized as a fluorescence-based sensor for various nitroaromatics including picric acid, for which an INHIBIT logic gate can also be constructed. The as synthesized complex was subsequently used as a fluorescent probe for imaging of human breast adenocarcinoma (MCF7) cells using live cell confocal microscopic techniques.
Topics & Concepts
Picric acidPyrazoleTurn (biochemistry)ChemistryPyridineCellCombinatorial chemistryCancer researchBiochemistryStereochemistryOrganic chemistryMedicineMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniquesLuminescence and Fluorescent Materials