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MF-094, a potent and selective USP30 inhibitor, accelerates diabetic wound healing by inhibiting the NLRP3 inflammasome

Xu Li, Tao Wang, Tao Yue, Xiaojun Wang, Limeng Li, Jianjun Liu

2021Experimental Cell Research33 citationsDOI

Topics & Concepts

Wound healingViability assayInflammasomeDownregulation and upregulationDiabetic footStreptozotocinGlycationDiabetes mellitusGene knockdownWestern blotBiologyPharmacologyImmunologyMedicineCancer researchApoptosisInflammationEndocrinologyBiochemistryGeneInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideAdvanced Glycation End Products research
MF-094, a potent and selective USP30 inhibitor, accelerates diabetic wound healing by inhibiting the NLRP3 inflammasome | Litcius