Enhancing the antioxidant capacity of Fe single-atom nanozymes through local coordination manipulation for psoriasis treatment
Hongjin Xue, Yunqian Li, Xinyu Ma, Yuanfeng Qi, Junkai Zhu, Xiang Ni, Jianfeng Qiu, Zhengjun Li, Zhen Mu
Abstract
nanozyme exhibited remarkable therapeutic effects with extremely low cytotoxicity, effectively inhibiting pathological epidermal proliferation, downregulating key inflammatory factors, and reducing the expression levels of psoriasis-associated pathway proteins. This work highlights the promise of single-atom nanozymes in the curing of inflammatory skin diseases, advancing the transformative role of nanotechnology in biomedicine.
Topics & Concepts
Atom (system on chip)PsoriasisAntioxidant capacityChemistryAntioxidantNanotechnologyMaterials scienceMedicineDermatologyComputer scienceOrganic chemistryEmbedded systemAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsElectrochemical sensors and biosensors