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The signal peptide as a new target for drug design

Liezel A. Lumangtad, Thomas W. Bell

2020Bioorganic & Medicinal Chemistry Letters48 citationsDOIOpen Access PDF

Topics & Concepts

Endoplasmic reticulumTransloconSec61Signal peptideChemistryCell biologyMembrane proteinSecretory proteinTranslation (biology)Small moleculeSecretory pathwayPeptideTransport proteinSecretionBiochemistryMembraneBiologyPeptide sequenceGolgi apparatusMessenger RNAGeneEndoplasmic Reticulum Stress and DiseaseCellular transport and secretionRNA Interference and Gene Delivery
The signal peptide as a new target for drug design | Litcius