Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival
Shawn Kothari, Andrew Artz, Sang Mee Lee, Noreen Fulton, Jae‐Hyun Park, Wendy Stock, Richard A. Larson, Olatoyosi Odenike, Justin Kline, James L. LaBelle, Satyajit Kosuri, Peter A. Riedell, Yusuke Nakamura, Michael R. Bishop, Hongtao Liu
Topics & Concepts
MedicineAlemtuzumabDonor lymphocyte infusionTransplantationImmunosuppressionInternal medicineHematopoietic stem cell transplantationLymphocyteSurgeryHematopoietic Stem Cell TransplantationT-cell and B-cell ImmunologyImmune Cell Function and Interaction