Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery
Mingyang Zhang, Xiaobing Lan, Xiaolong Li, Shaoyong Lu
Topics & Concepts
Allosteric regulationG protein-coupled receptorIntracellularDrug discoverySignal transductionBiologyExtracellularReceptorAllosteric modulatorStructural biologyCell biologyComputational biologyBioinformaticsBiochemistryReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyMass Spectrometry Techniques and Applications