The lncRNAs LINC00261 and LINC00665 are upregulated in long-term prostate cancer adaptation after radiotherapy
Iris Eke, Michelle A. Bylicky, Veit Sandfort, Sunita Chopra, Shannon Martello, Edward E. Graves, C. Norman Coleman, Molykutty J. Aryankalayil
Abstract
. Identifying long-term tumor adaptation mechanisms can lead to the discovery of new molecular targets, in effect opening up new research directions and improving multimodal radiation oncologic treatment.
Topics & Concepts
Prostate cancerGene knockdownCancer researchRadiation therapyDownregulation and upregulationDNA repairmicroRNABiologyDNA damageLong non-coding RNACancerGenome instabilityOncologyMedicineInternal medicineDNAGeneGeneticsCancer-related molecular mechanisms researchNuts composition and effectsCircular RNAs in diseases