A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins
Sriram Aiyer, G.V.T. Swapna, Li-Chung Ma, Gaohua Liu, Jingzhou Hao, Gordon Chalmers, Brian C. Jacobs, G.T. Montelione, Monica J. Roth
Topics & Concepts
LinkerSH3 domainBiologyViral proteinIntegrasePlasma protein bindingBinding domainBinding siteCell biologyGeneticsDNAVirusReceptorProto-oncogene tyrosine-protein kinase SrcComputer scienceOperating systemProtein Degradation and InhibitorsHIV Research and TreatmentHIV/AIDS drug development and treatment