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Whole-Genome Sequencing and Comparative Genome Analysis of Fusarium solani-melongenae Causing Fusarium Root and Stem Rot in Sweetpotatoes

Shu-Yan Xie, Tingting Ma, Nan Zhao, Xinxin Zhang, Boping Fang, Lifei Huang

2022Microbiology Spectrum31 citationsDOIOpen Access PDF

Abstract

Fusarium root and stem rot in sweetpotato are prevalent in the main sweetpotato-growing areas in China, and fungal isolation, morphological characteristics, and molecular phylogenetic analysis of the disease causal agent (F. solani-melongenae isolate CRI 24-3) were systematically studied. The genome sequence of F. solani-melongenae isolates CRI 24-3 was first reported, which should provide a basis for genome assembly of other closely related Fusarium species. Carbohydrate-active enzymes predicted in CRI 24-3 may be important to convert the substantial polysaccharides to sustainable and renewable energy. Moreover, other virulence factors facilitating Fusarium diseases, including effectors and toxic secondary metabolites, are ideal objects for pathogenicity mechanism research and molecular targets for fungicide development. The findings of comparative genome analysis of CRI 24-3 and 15 sequenced members of the F. solani species complex help promote an integral understanding of genomic features and evolutionary relationships in Fusarium.

Topics & Concepts

BiologyFusarium solaniGenomeFusariumPhylogenetic treeWhole genome sequencingGeneticsGeneBotanyPlant Pathogens and Fungal DiseasesPlant-Microbe Interactions and ImmunityMycorrhizal Fungi and Plant Interactions