Targets and underlying mechanisms related to the sedative and hypnotic activities of saponins from <i>Rhodiola rosea</i> L. (crassulaceae)
Yun-Fang Hao, Ting Luo, Zhongyu Lu, Chunyan Shen, Jian‐Guo Jiang
Abstract
HJT-I and HJT-II exert sedative–hypnotic effects by modulating the 5-HTergic, GABA A ergic and immune systems in PCPA-induced rats. HJT-II with a higher saponin content was more effective.
Topics & Concepts
Rhodiola roseaCrassulaceaeRhodiolaHypnoticTraditional medicinePharmacologySedativeSalidrosideMedicineBiologyBotanyMedicinal Plants and Bioactive CompoundsPharmacological Effects of Natural CompoundsGinseng Biological Effects and Applications