Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy
Ruth M. Saecker, Mueller AU, Brandon Malone, James Chen, William C. Budell, Venkata P. Dandey, Kashyap Maruthi, Joshua H. Mendez, N Molina, Edward T. Eng, Laura Y. Yen, Clinton S. Potter, Bridget Carragher, Seth A. Darst
Topics & Concepts
Cryo-electron microscopyRNA polymerasePolymeraseElectron microscopeBiophysicsChemistryCell biologyMicroscopyRNARNA polymerase IIBiologyCrystallographyMolecular biologyDNAPromoterBiochemistryGene expressionGenePhysicsOpticsRNA and protein synthesis mechanismsBacterial Genetics and BiotechnologyAdvanced Electron Microscopy Techniques and Applications