Ca2+-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak
Giovanni Quarato, Fabien Llambi, Cliff Guy, Jaeki Min, Marisa Actis, Huan Sun, Shilpa Narina, Shondra M. Pruett‐Miller, Junmin Peng, Zoran Ranković, Douglas R. Green
Topics & Concepts
CytosolCell biologyProgrammed cell deathIntracellularMitochondrial permeability transition poreMitochondrionEndoplasmic reticulumMitochondrial apoptosis-induced channelInner mitochondrial membraneBAPTABiologyOrganelleMitochondrial membrane transport proteinApoptosisBiochemistryEnzymeMitochondrial Function and PathologyATP Synthase and ATPases ResearchCell death mechanisms and regulation